Evaluation of anti-inflammatory, analgesic activities, and side effects of some pyrazole derivatives.

Souraya A DomiatiAhmed El-MallahAsser GhoneimAdnan BekhitHeba Abd El Razik

Published in: Inflammopharmacology (2016)

As a conclusion, from the ten compounds analyzed, N5 and N7 showed promising results as anti-inflammatory/analgesic agents with low ulcerogenicity and nephrotoxicity and thus should be further analyzed to determine the ED50 and other side effects.

Keyphrases

anti inflammatory
emergency department
molecular docking
spinal cord injury
molecular dynamics simulations