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Evaluation of anti-inflammatory, analgesic activities, and side effects of some pyrazole derivatives.

Souraya A DomiatiAhmed El-MallahAsser GhoneimAdnan BekhitHeba Abd El Razik
Published in: Inflammopharmacology (2016)
As a conclusion, from the ten compounds analyzed, N5 and N7 showed promising results as anti-inflammatory/analgesic agents with low ulcerogenicity and nephrotoxicity and thus should be further analyzed to determine the ED50 and other side effects.
Keyphrases
  • anti inflammatory
  • emergency department
  • molecular docking
  • spinal cord injury
  • molecular dynamics simulations