Large tumoral pseudoangiomatous stromal hyperplasia with ER/PR stromal negativity in a 20-year-old female: A rare case report.

Somar Mansour Seif-Aldin Abdul Rahman Ali Kazour Ibrahim Salama Hussain Shmayes Samer Rajab Rana Issa

Published in: Clinical case reports (2024)

Pseudoangiomatous stromal hyperplasia (PASH) is a rare lesion of the breast stromal tissue with unknown mechanism. Hormonal stimulation of mammary myofibroblasts is the most important theory due to stromal positivity of progesterone receptor (PR) or/and estrogen receptor (ER). We report a case of PASH with stromal PR/ER negativity.

Keyphrases

estrogen receptor
bone marrow
case report
endoplasmic reticulum
breast cancer cells
skeletal muscle