A light-responsive liposomal agent for MRI contrast enhancement and monitoring of cargo delivery.
F ReeßingMarc C A StuartD F SamploniusR A J O DierckxBen L FeringaW HelfrichWiktor SzymanskiPublished in: Chemical communications (Cambridge, England) (2019)
Medical magnetic resonance imaging (MRI) produces high-resolution anatomical images of the human body, but has limited capacity to provide useful molecular information. The light-responsive, liposomal MRI contrast agent described herein could be used to provide an intrinsic theranostic aspect to MRI and enable tracking the distribution and cargo release of drug delivery systems upon light-triggered activation.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- diffusion weighted imaging
- magnetic resonance
- high resolution
- computed tomography
- endothelial cells
- healthcare
- cancer therapy
- deep learning
- photodynamic therapy
- mass spectrometry
- convolutional neural network
- fluorescence imaging
- optical coherence tomography
- health information
- machine learning