Adding Induction Chemotherapy Before Chemoradiotherapy with Total Mesorectal Excision and Selective Lateral Lymph Node Dissection for Patients with Poor-Risk, Locally Advanced, Mid-to-Low Rectal Cancer May Improve Oncologic Outcomes: A Propensity Score-Matched Analysis.
Tomohiro YamaguchiTakashi AkiyoshiYosuke FukunagaTakashi SakamotoToshiki MukaiYukiharu HiyoshiToshiya NagasakiSenzo TaguchiAkiko ChinoEiji ShinozakiKensei YamaguchiTsuyoshi KonishiPublished in: Annals of surgical oncology (2023)
The addition of induction chemotherapy to neoadjuvant CRT appeared to improve oncologic outcomes significantly, including disease-free survival, for the patients with poor-risk, mid-to-low rectal cancer who underwent TME using selective lateral lymph node dissection.