Management of Lupus Nephritis: New Treatments and Updated Guidelines.

Rupali Avasare Yelena DrexlerDawn J CasterAlla MitrofanovaJ Ashley Jefferson

Published in: Kidney360 (2023)

Management of lupus nephritis (LN) has evolved considerably over the past years. Here we provide a comprehensive review of clinical trials that form the basis for the KDIGO and EULAR/ERA-EDTA updated guidelines and present-day trials that will change the landscape of LN therapy in years to come. Additionally, we highlight issues related to cost of therapy, resistant disease, and downstream adverse effects of specific therapies.

Keyphrases

clinical trial
clinical practice
stem cells
emergency department
single cell
mesenchymal stem cells
phase ii
double blind
replacement therapy
electronic health record