Risk of recurrence after local resection of T1 rectal cancer: a meta-analysis with meta-regression.

Nik DekkersHao DangJolein van der KraanSaskia le CessiePhilip P OldenburgJan W SchoonesAlexandra M J LangersMonique E van LeerdamJeanin E van HooftYara BackesKatarina LevicAlexander MeiningGiorgio M SaraccoFabian A HolmanKoen C M J PeetersLeon M G MoonsPascal G DoorneboschJames C H HardwickJurjen J Boonstra

Published in: Surgical endoscopy (2022)

Patients with T1 rectal cancer may have a significantly lower recurrence risk after TEM/TAMIS compared to other local surgical resection techniques. After TEM/TAMIS and endoscopic resection the recurrence risk, cancer-related mortality and cancer-related mortality among patients with recurrence were comparable. Recurrence was mainly dependent on histological risk status.

Keyphrases

rectal cancer
free survival
locally advanced
cardiovascular events
squamous cell carcinoma
risk factors
type diabetes
cardiovascular disease
radiation therapy