High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial.

Indika Bandara Gawarammana Nicholas Alan Buckley Fahim MohamedKamal NaserK JeganathanP L AriyananadaKlintean WunnapukTimothy A DobbinsJohn A TomensonMartin F WilksMichael Eddleston Andrew H Dawson

Published in: Clinical toxicology (Philadelphia, Pa.) (2017)

We found no evidence that high dose immunosuppression improves survival in paraquat-poisoned patients. The continuing high mortality means further research on the use of dexamethasone and other potential treatments is urgently needed.

Keyphrases

high dose
low dose
stem cell transplantation
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
risk factors
cardiovascular disease