Ectopic endometriosis in the pelvic cavity evokes bladder hypersensitivity via transient receptor potential ankyrin 1 hyperexpression in rats.

Natsuho HayashiNaoki KawamoritaYuichi IshizukaShingo KimuraYohei SatakeAkihiro Ito

Published in: International urogynecology journal (2022)

Bladder cross-sensitization in ENDO rats occurs in association with hyperexpression of TRPA1 at both the DRG and the bladder mucosa. This can be understood by the "cross-sensitization of endometriosis to bladder" theory explaining overlapping symptoms among BPS/IC and ectopic endometriosis.

Keyphrases

spinal cord injury
urinary tract
physical activity
risk assessment
drug induced
sleep quality
depressive symptoms