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Catecholamines production by kidney tissue and mesangial cell culture is differentially modulated by diabetes.

Roseli Peres MoreiraNadia S C BertoncelloJuliana Almada ColucciDanielle Yuri AritaMaria Claudina Camargo de AndradeFernanda Aparecida RonchiTatiana Sousa CunhaDulce Elena Casarini
Published in: Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia (2021)
The major finding of the present study was that 8 weeks of diabetes induction altered the kidney catecholaminergic system in a very specific manner, once the production of catecholamines in the excised kidney tissue from diabetic rats was differentially modulated as compared with the production and secretion by cultured mesangial cells.
Keyphrases
  • diabetic rats
  • type diabetes
  • cardiovascular disease
  • induced apoptosis
  • oxidative stress
  • glycemic control
  • high glucose
  • endothelial cells
  • insulin resistance
  • adipose tissue
  • endoplasmic reticulum stress
  • cell death