A Principal Component of Quality of Life Measures Is Associated with Survival for Head and Neck Cancer Patients Treated with Radiation Therapy.
Mark K FarrugiaHan YuSung Jun MaAustin J IovoliKristopher AttwoodKimberly E WootenHassan ArshadVishal GuptaRyan P McSpaddenMoni A KuriakoseMichael R MarkiewiczJon M ChanWesley L HicksMary E PlatekAndrew D RayElizabeth A RepaskyAnurag K SinghPublished in: Cancers (2021)
Our study provides evidence that post-treatment recovery of HRQOL domains were associated with overall survival (OS) in HNC. PC1 is an attractive clinical tool to assess the recovery across multiple different HRQOL and the relationship with survival. Future prospective studies may identify patients who could benefit from additional rehabilitation based on PC1 score.