Metamizole inhibits arachidonic acid-induced platelet aggregation after surgery and impairs the effect of aspirin in hospitalized patients.

Christian PfrepperS DetersM MetzeR SiegemundI GockelS Petros

Published in: European journal of clinical pharmacology (2019)

The reason why some patients have a long-lasting inhibitory effect of metamizole on COX-induced platelet aggregation that might interfere with ASA should be investigated in a larger cohort of patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
low dose
peritoneal dialysis
cardiovascular disease
patient reported outcomes
acute coronary syndrome
high resolution
cardiovascular events
drug induced