Urinary CD4+ T cells Predict Renal Relapse in ANCA-Associated Vasculitis: Results of the PRE-FLARED Study.
Luka PrskaloChristopher Mark SkopnikNina GoerlichPaul FreundLeonie WagnerEmil GrothgarPouneh MirkheshtiJan KlockeJanis SonnemannDiana MetzkeUdo SchneiderFalk HiepeKai Uwe EckardtAlan David SalamaMarkus BieringerAdrian SchreiberPhilipp EnghardPublished in: Journal of the American Society of Nephrology : JASN (2024)
The study concluded that urinary CD4+ T cell counts could identify AAV patients at a substantial risk of renal relapse within six months. Combining these counts with ANCA levels further improved the prediction of relapse. These findings have implications for personalized management strategies in patients with renal AAV.
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