Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients.
Yanhua CuiFemke HarteveldHajar Ali Mohammed Ba OmarYifan YangRagnar BjarnasonPatrik RomeriusMikael SundinUlrika Norén NyströmCecilia LangenskiöldHartmut VogtLars HenningsohnPer FriskKaisa VepsäläinenCecilia PetersenRod Thomas MitchellJingtao GuoJoão Pedro Alves-LopesKirsi JahnukainenJan-Bernd StukenborgPublished in: Human reproduction open (2024)
This study was supported by grants from the Swedish Childhood Cancer Foundation (PR2019-0123; PR2022-0115; TJ2020-0023) (J.-B.S.), Finnish Cancer Society (K.J.), Finnish Foundation for Paediatric Research (K.J.), Swedish Research Council (2018-03094; 2021-02107) (J.-B.S.), and Birgitta and Carl-Axel Rydbeck's Research Grant for Paediatric Research (2020-00348; 2020-00335; 2021-00073; 2022-00317) (J.-B.S. and K.J.). Y.C. and Y.Y. received a scholarship from the Chinese Scholarship Council. J.P.A-L. was supported by a Starting Grant in Medicine and Health (2022-01467) from the Swedish Research Council. R.T.M. was supported by a UKRI Future Leaders Fellowship (MR/S017151/1). The MRC Centre for Reproductive Health was supported by an MRC Centre Grant (MR/N022556/1). The authors declare no competing interests.
Keyphrases
- childhood cancer
- young adults
- intensive care unit
- emergency department
- induced apoptosis
- public health
- healthcare
- magnetic resonance
- contrast enhanced
- mental health
- papillary thyroid
- magnetic resonance imaging
- health information
- cell cycle arrest
- oxidative stress
- risk assessment
- squamous cell carcinoma
- squamous cell
- current status
- social media
- health promotion