Explore the shared molecular mechanism between dermatomyositis and nasopharyngeal cancer by bioinformatic analysis.
Xiuqin ZhongJingjing ShangRongwei ZhangXiuling ZhangLe YuHaitao NiuXin-Wang DuanPublished in: PloS one (2024)
Our research discovered pivot genes between DM and NPC. Viral gene replication and response to type I interferon may be the crucial bridge between DM and NPC. By regulating hub genes, MiR-146a will provide new strategies for diagnosis and treatment in DM complicated by NPC patients. For individuals with persistent viral replication in DM, screening for nasopharyngeal cancer is necessary.
Keyphrases
- papillary thyroid
- genome wide
- genome wide identification
- sars cov
- squamous cell
- end stage renal disease
- bioinformatics analysis
- ejection fraction
- glycemic control
- cell proliferation
- newly diagnosed
- long non coding rna
- type diabetes
- prognostic factors
- dendritic cells
- squamous cell carcinoma
- genome wide analysis
- gene expression
- long noncoding rna
- disease activity
- childhood cancer
- young adults
- adipose tissue
- immune response
- network analysis