The effect of tuberculosis on immune reconstitution among HIV patients on highly active antiretroviral therapy in Adigrat general hospital, eastern Tigrai, Ethiopia; 2019: a retrospective follow up study.
Hadush Negash MelesHaftom LegeseMebrahtu TeferaFitsum MarduKebede TesfaySenait GebresilasieBerhane FsehaTsega KahsayAderajew GebrewahdBrhane BerhePublished in: BMC immunology (2019)
There was a high rate of CD4+ T cells reconstitution failure among our study participants. Tuberculosis infection increased the rate of failure. Factors like low CD4+ T cell baseline count, poor adherence and urban residence were associated with the immunological failure. There should be strict monitoring of CD4+ T cell counts among individuals with tuberculosis coinfection.
Keyphrases
- antiretroviral therapy
- hiv aids
- mycobacterium tuberculosis
- hiv infected
- hiv positive
- human immunodeficiency virus
- end stage renal disease
- pulmonary tuberculosis
- ejection fraction
- hiv infected patients
- adverse drug
- newly diagnosed
- chronic kidney disease
- hepatitis c virus
- peritoneal dialysis
- south africa
- peripheral blood
- type diabetes
- emergency department
- patient reported outcomes
- glycemic control