An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers.
Junnian WeiYung-Hua WangChia Yin LeeCharles TruilletDavid Y OhYichen XuDavide RuggeroRobert R FlavellHenry F VanBrocklinYoungho SeoCharles S CraikLawrence FongCheng-I WangKenneth W BaylesPublished in: Molecular imaging and biology (2020)
In summary, these data support the use of low molecular weight constructs for PD-L1 imaging, especially for tumor types that manifest in abdominal organs that are obstructed by the clearance of high molecular weight radioligands.