CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells' Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy.
Jian WangYing ZhouLi MaShannan CaoWei GaoQingqing XiongKaiyuan WangLili YangPublished in: Oxidative medicine and cellular longevity (2019)
Thus, the current results implied a potential management by which CIAPIN1 upregulation may have a crucial effect on the suppression of NSCLC, indicating that overexpression of CIAPIN1 might serve as a combination with chemotherapeutical agents in NSCLC therapy.
Keyphrases
- small cell lung cancer
- advanced non small cell lung cancer
- cell proliferation
- brain metastases
- signaling pathway
- induced apoptosis
- epidermal growth factor receptor
- pi k akt
- stem cells
- transcription factor
- oxidative stress
- mesenchymal stem cells
- cancer therapy
- long non coding rna
- endoplasmic reticulum stress
- bone marrow