Group B Streptococcus early-onset disease and observation of well-appearing newborns.
Alberto BerardiCaterina SpadaMaria Letizia Bacchi ReggianiRoberta CretiLorenza BaroniMaria Grazia CaprettiMatilde CicciaValentina FioriniLucia GambiniGiancarlo GarganoIrene PapaGiancarlo PiccininiVittoria RizzoFabrizio SandriLaura Lucaccioninull nullPublished in: PloS one (2019)
Infants with EOS exposed to IAP developed symptoms at birth in almost all cases, and those who appeared well at birth had a very low chance of having EOS. The risk of EOS in neonates (asymptomatic at birth) exposed to intrapartum fever was low. Although definite conclusions on causation are lacking, our data support SPEs of asymptomatic newborns at risk for EOS. SPEs seems a safe and effective alternative to laboratory screening and empirical antibiotic therapy.