Omeprazole Induced Rapid Drug Reaction with Eosinophilia, Systemic Symptoms, and Cross-Reactivity in Delayed-Type Hypersensitivity Associated with Proton-Pump Inhibitors: A Case Report and Literature Review.

Kanokkarn Pinyopornpanish Kanokporn Pinyopornpanish Kanokwan Pinyopornpanish Juthipong Benjanuwattra Putthapon TeepapanApinya ChungcharoenpanichWannada Laisuan

Published in: Case reports in immunology (2024)

PPI is commonly used safely as an agent for acid-related gastrointestinal conditions. However, PPI-induced rapid DRESS syndrome can occur, particularly with prior exposure history. ELISpot is an in vitro test, useful in identifying the culprit agent in patients with delayed-type hypersensitivity reaction.

Keyphrases

drug induced
high glucose
diabetic rats
protein protein
oxidative stress
endothelial cells
emergency department
case report
adverse drug
physical activity
stress induced