MSC-derived small extracellular vesicles alleviate diabetic retinopathy by delivering miR-22-3p to inhibit NLRP3 inflammasome activation.

Yueqin ChenGenhong YaoJun TongHairong XieXinyu ZhengHuayong ZhangZhenggao Xie

Published in: Stem cells (Dayton, Ohio) (2023)

These results indicated that MSC-sEVs alleviated DR via delivering miR-22-3p to inhibit NLRP3 inflammasome activation. Our findings indicate that MSC-sEVs might be a potential therapeutic method for DR.

Keyphrases

nlrp inflammasome
diabetic retinopathy
optical coherence tomography
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