Non-invasive liver fibrosis scores are strongly associated with liver cancer mortality in general population without liver disease.
Ki Chul SungMichael P JohnstonMi-Yeon LeeChristopher D ByrnePublished in: Liver international : official journal of the International Association for the Study of the Liver (2020)
In a general population without known liver disease, high FIB-4 or high APRI (in keeping with a high probability of advanced fibrosis) occurred in 0.25% (FIB-4) and 0.09% (APRI) of subjects. Both scores were associated with a markedly increased risk of liver cancer mortality and FIB-4 and APRI models both strongly predicted liver cancer mortality.