Role of Exosomes Derived from Adipose Tissue under Obese Conditions in Skeletal Muscle and Liver Cells: Commonalities and Differences.
Yujeong KimTaesang SonJeongjin ParkWoojin JunOk-Kyung KimPublished in: Molecular nutrition & food research (2022)
The results suggest that Ad-exosomes from HFD-fed obese mice cause insulin resistance in both the muscles and liver, but their effects on metabolism during the development of insulin resistance vary between tissues.
Keyphrases
- insulin resistance
- adipose tissue
- high fat diet
- skeletal muscle
- mesenchymal stem cells
- metabolic syndrome
- induced apoptosis
- stem cells
- polycystic ovary syndrome
- type diabetes
- cell cycle arrest
- high fat diet induced
- gene expression
- weight loss
- cell death
- bone marrow
- cell proliferation
- signaling pathway
- endoplasmic reticulum stress
- glycemic control
- obese patients