"Brain age" predicts disability accumulation in multiple sclerosis.

Matthew R BrierZhuocheng LiMaria LyHelmet T KarimLeda LiangWeixin DuJohn E McCarthyAnne H Cross Tammie L S BenzingerRobert T NaismithSalim Chahin

Published in: Annals of clinical and translational neurology (2023)

Brain age is a technically tractable and clinically relevant biomarker of disease pathology that correlates with and predicts increasing disability in MS. Advanced brain age predicts future disability accumulation.

Keyphrases

multiple sclerosis
white matter
resting state
functional connectivity
cerebral ischemia