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Society of pediatric liver transplantation: Current registry status 2011-2018.

Scott A ElisofonJohn C MageeVicky Lee NgSimon Peter HorslenVicki FioravantiJulie EconomidesJinson ErinjeriRavinder AnandGeorge Vincent Mazariegosnull null
Published in: Pediatric transplantation (2019)
A total of 1911 recipients from 39 participating centers in North America were registered. Indications included biliary atresia (38.5%), metabolic disease (19.1%), tumors (11.7%), and fulminant liver failure (11.5%). Greater than 50% of recipients were transplanted as either Status 1A/1B or with a MELD/PELD exception score. Incompatible transplants were performed in 4.1%. Kaplan-Meier estimates of 1-year patient and graft survival were 97.3% and 96.6%. First 30 days of surgical complications included reoperation (31.7%), hepatic artery thrombosis (6.3%), and portal vein thrombosis (3.2%). In the first 90 days, biliary tract complications were reported in 13.6%. Acute cellular rejection during first year was 34.7%. At 1 and 2 years of follow-up, 39.2% and 50.6% had normal liver tests on monotherapy (tacrolimus or sirolimus). Further surgical, survival, allograft function, and complications are detailed.
Keyphrases
  • liver failure
  • hepatitis b virus
  • risk factors
  • pulmonary embolism
  • kidney transplantation
  • case report
  • study protocol
  • respiratory failure
  • extracorporeal membrane oxygenation