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Enriched Single-Nucleus RNA-Sequencing Reveals Unique Attributes of Distal Convoluted Tubule Cells.

Xiao-Tong SuJeremiah V ReyesAnne E LackeyHasan DemirciSebastian BachmannYujiro MaeokaRyan J CorneliusJames A McCormickChao-Ling YangHyun Jun JungPaul A WellingJonathan W NelsonDavid H Ellison
Published in: Journal of the American Society of Nephrology : JASN (2024)
Transcriptomic analysis of an enriched rare cell population using a genetically targeted approach clarifies the function and classification of distal cells. The DCT segment is short, yet, can be separated into two sub-segments that serve distinct functions, and are speculated to derive from different origins during development.
Keyphrases
  • induced apoptosis
  • single cell
  • cell cycle arrest
  • minimally invasive
  • machine learning
  • rna seq
  • endoplasmic reticulum stress
  • deep learning
  • stem cells
  • cell therapy
  • oxidative stress
  • mesenchymal stem cells
  • drug delivery