Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway.
Ruiting ShenPeng YinHua YaoLu ChenXinyu ChangHuanrong LiXiaolin HouPublished in: Journal of inflammation research (2021)
Punicalin ameliorates LPS/ATP-induced pyroptosis in J774A.1 macrophages, the mechanism may involve downregulation of the ROS/NLRP3 inflammasome signaling pathway.
Keyphrases
- nlrp inflammasome
- signaling pathway
- inflammatory response
- cell death
- dna damage
- reactive oxygen species
- anti inflammatory
- mouse model
- pi k akt
- single cell
- high glucose
- diabetic rats
- cell proliferation
- cell therapy
- epithelial mesenchymal transition
- induced apoptosis
- drug induced
- stem cells
- endothelial cells
- bone marrow