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Multifunctional ROS-Responsive and TME-Modulated Lipid-Polymer Hybrid Nanoparticles for Enhanced Tumor Penetration.

Rui NiLele HuangZhen LiWenli ZhangYajie WangYan ShenJianxin WangWeigen Lu
Published in: International journal of nanomedicine (2022)
in tumor targeting, collagen inhibition in TME, and enhanced tumor penetration. This novel drug delivery system can therefore play a substantial role in improving the therapeutic efficacy of antitumor drugs combined with TME-improving agents.
Keyphrases
  • cancer therapy
  • drug delivery
  • dna damage
  • cell death
  • reactive oxygen species