4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression.

Chien-Hsin ChangChun-Chieh HsuAn-Sheng LeeShih-Wei WangKung-Tin LinWei-Luen ChangHui-Chin PengWen-Chiung HuangChing-Hu Chung

Published in: BMC complementary and alternative medicine (2018)

These results showed that 4AAQB exhibited anti-inflammatory property both in vitro and in vivo, suggesting that 4AAQB may be a therapeutic candidate which used in inflammatory disorders treatment.

Keyphrases

lipopolysaccharide induced
inflammatory response
signaling pathway
oxidative stress
anti inflammatory
lps induced
pi k akt
intensive care unit
acute kidney injury
nuclear factor
mouse model
toll like receptor
immune response