PBPK Analysis to Study the Impact of Genetic Polymorphism of NAT2 on Drug-Drug Interaction Potential of Isoniazid.

Published in: Pharmaceutical research (2021)

The novel outcome of the present study is the indication that prescribers should give careful consideration while advising CYP2C19 and CYP3A4 substrate drugs to subjects who are on prophylaxis INH therapy, and are slow to metabolic acetylation.

Keyphrases

mycobacterium tuberculosis
emergency department
stem cells
bone marrow
climate change
dna methylation