Characteristic of Molecular Subtypes in Lung Squamous Cell Carcinoma Based on Autophagy-Related Genes and Tumor Microenvironment Infiltration.
Jinjie WangJiaqi ZhuYijie TangAnping ZhangTingting ZhouYou Lang ZhouJia-Hai ShiPublished in: Journal of oncology (2022)
This study explored the autophagy molecular subtypes in LUSC. We also discovered the heterogeneity of TME cell infiltration driven by autophagy-related genes. The established APS model is of great significance for evaluating the prognosis of LUSC patients, the infiltration of TME cells, and the effect of immunotherapy.
Keyphrases
- endoplasmic reticulum stress
- cell death
- induced apoptosis
- squamous cell carcinoma
- signaling pathway
- end stage renal disease
- oxidative stress
- single cell
- cell cycle arrest
- chronic kidney disease
- newly diagnosed
- ejection fraction
- peritoneal dialysis
- prognostic factors
- single molecule
- pi k akt
- locally advanced
- patient reported