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BRCA2, PALB2, RECQL4 Germline Pathogenic Variants, and Somatic TP53 Mutation in Triple Metachronous Malignancies: A Case Report and Literature Review.

Yang LiuHui YangXueshu FuLuting ZhongPing XuFang FangYing LiuQing LiYa'nan YanShanchuang WeiJunqing WangChunhua Zhang
Published in: International medical case reports journal (2024)
Genetic testing may be imperative for identifying MPC in endometrial cancer patients. For individuals with BRCA2 and other gene pathogenic variants, routine examination and monitoring of the endometrium, ovaries, breasts, and other sites prone to polygenic cancer are recommended.
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