Hemorrhagic shock induces renal complement activation.
Christian EhrnthallerAnke SchultzeGamal WakilehThomas NeffSebastian HafnerPeter RadermacherMarkus Huber-LangPublished in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2019)
The more pronounced complement activation centrally might indicate consumption of complement products in kidney tissue, which is underlined by C3c staining. Together with diminished levels of zonulin in both systemic and local samples, results could indicate the involvement of complement as well as zonulin in acute kidney failure.