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Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region.

Kristina M JordahlAnna ShcherbinaAndre E KimYu-Ru SuYi LinJun WangConghui QuDemetrius AlbanesVolker ArndtJames W BaurleySonja I BerndtStephanie A BienD Timothy BishopEmmanouil BourasHermann BrennerDaniel D BuchananArif BudiartoPeter T CampbellRobert Carreras-TorresGraham CaseyTjeng Wawan CenggoroAndrew T ChanDavid V ContiChristopher H DampierMatthew A DevallVirginia Díez-ObreroNiki L DimouDavid A DrewJane C FigueiredoSteven GallingerGraham G GilesStephen B GruberAndrea GsurMarc J GunterHeather HampelSophia HarlidTabitha A HarrisonAkihisa HidakaMichael HoffmeisterJeroen R HuygheMark A JenkinsAmit D JoshiTemitope O KekuSusanna C LarssonLoic Le MarchandJuan Pablo LewingerLi LiBharuno MahesworoVictor MorenoJohn L MorrisonNeil MurphyHongmei NanRami NassirPolly A NewcombMireia Obón-SantacanaShuji OginoJennifer OseRish K PaiJulie R PalmerNikos PapadimitriouBens PardameanAnita R PeoplesPaul D P PharoahElizabeth A PlatzJohn D PotterRoss L PrenticeGadi RennertEdward A Ruiz-NarvaezLori C SakodaPeter C ScacheriStephanie L SchmitRobert E SchoenMartha L SlatteryMariana C SternCatherine M TangenStephen N ThibodeauDuncan C ThomasYu TianKonstantinos K TsilidisCornelia M UlrichFranzel J B van DuijnhovenBethany Van GuelpenKala VisvanathanPavel VodickaEmily WhiteAlicja WolkMichael O WoodsAnna H WuNatalia ZemlianskaiaJenny Chang-ClaudeW James GaudermanLi HsuAnshul KundajeUlrike Peters
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)
The study identifies multifaceted evidence of a possible functional effect for rs1318920.
Keyphrases
  • alcohol consumption
  • genome wide
  • gene expression
  • dna methylation