PBP-3 Directed Therapy in VIM-producing Pseudomonas aeruginosa Creates Bacterial Transformers, Persisters in Disguise.
Nicholas M SmithKatie Rose BoissonneaultPatricia N HoldenJan Naseer KaurJack F KlemRaymond ChaMark D SuttonBrian T TsujiPublished in: International journal of antimicrobial agents (2024)
Managing MBL-producing P. aeruginosa requires a multifaceted approach, focused on maximising killing and minimising proliferation of resistant and persistent subpopulations, which will involve eliminating drug-induced phenotypic transformers.