Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of Xiao Yao san on chronically stressed mice.

Xiu-Fang DingYue-Hua LiJia-Xu ChenLong-Ji SunHai-Yan JiaoXin-Xin WangYan Zhou

Published in: BMC complementary and alternative medicine (2017)

The studies indicated that XYS may have therapeutic actions on depression -like behavior s induced by CUMS in mice possibly mediated by modulation of glutamate/glutamine cycle and glutamate transporter GLT-1 in the hippocampus.

Keyphrases

high fat diet induced
depressive symptoms
insulin resistance
type diabetes
sleep quality
metabolic syndrome
wild type