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Potential impact of unblinding on observed treatment effects in Alzheimer's disease trials.

Sirwan K L DarweeshJeremy A Labrecque
Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Psychological treatment effects due to unblinding may explain a substantial share of observed treatment effects in RCTs.
Keyphrases
  • physical activity
  • replacement therapy
  • patient reported