Epigenetic marker of telomeric age is associated with exacerbations and hospitalizations in chronic obstructive pulmonary disease.

Ana I Hernández CorderoChen Xi YangXuan LiStephen MilneVirginia ChenZsuzsanna HollanderRaymond NgGerard J CrinerPrescott G WoodruffStephen C LazarusJohn E ConnettMeiLan K HanFernando J MartinezRobert M ReedS F Paul ManJanice M LeungDon D Sin

Published in: Respiratory research (2021)

Telomeric age based on blood DNA methylation is associated with COPD exacerbation and hospitalization and thus a promising biomarker for poor outcomes in COPD.

Keyphrases

chronic obstructive pulmonary disease
dna methylation
lung function
gene expression
dna damage response
genome wide
cystic fibrosis
adipose tissue
air pollution
insulin resistance
acute respiratory distress syndrome