Inhibition of oocyte maturation by follicular extracellular vesicles of non-hyperandrogenic PCOS patients requiring IVF.

Chang LiuMeng WangHaixia YaoMengge CuiXueqi GongLan WangCong SuiHanwang Zhang

Published in: The Journal of clinical endocrinology and metabolism (2022)

PCOS-EVs interfered with oocyte mitochondria and spindles and inhibited oocyte maturation. Moreover, oxidative stress induced by PCOS-EVs might be a potential cause.

Keyphrases

polycystic ovary syndrome
oxidative stress
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
cell death
type diabetes
pregnant women
insulin resistance
ischemia reperfusion injury
pregnancy outcomes