Knockdown resistance (kdr) gene of Aedes aegypti in Malaysia with the discovery of a novel regional specific point mutation A1007G.

Mas Azlin M AkhirMustafa F F WajidiSébastien LavouéGhows AzzamIzhan Shahrin JaafarNoor Aslinda Ummi Awang BesarIntan Haslina Ishak

Published in: Parasites & vectors (2022)

This study revealed the high resistance level of Malaysian populations of Ae. aegypti to currently used insecticides. The resistance could be due to the widespread presence of four kdr mutations in the field and this could potentially impact the vector control programmes in Malaysia and alternative solutions should be sought.

Keyphrases

aedes aegypti
zika virus
dengue virus
small molecule
single cell
high throughput
gene expression
transcription factor