Loss of whole chromosome X predicts prognosis of neuroblastoma patients with numerical genomic profile.

Stefano ParodiAngela PistorioGiovanni ErminioMarzia OgnibeneMartina MoriniAlberto GaraventaAnna Rita GigliottiRiccardo HauptFrancesco FrassoniAnnalisa Pezzolo

Published in: Pediatric blood & cancer (2019)

Loss of whole chromosome X may represent a new prognostic marker for NB patients with an NCA genomic profile. If confirmed by further studies, this finding could indicate that such patients should be reclassified as intermediate risk and treated accordingly.

Keyphrases

copy number
newly diagnosed
end stage renal disease
ejection fraction
prognostic factors
peritoneal dialysis
gene expression
dna methylation
patient reported