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The tal gene of lactococcal bacteriophage TP901-1 is involved in DNA release following host adsorption.

Sofía Ruiz-CruzAndrea Erazo GarzonChristian CambillauGuillermo Ortiz CharnecoGabriele Andrea LugliMarco VenturaJennifer MahonyDouwe Van Sinderen
Published in: Applied and environmental microbiology (2024)
3107. Specifically, we have found that three amino acid changes in Tal appear to facilitate structural rearrangements in the baseplate necessary for the DNA release process, even in the absence of an otherwise required host trigger.
Keyphrases
  • circulating tumor
  • amino acid
  • cell free
  • single molecule
  • genome wide
  • copy number
  • dna methylation
  • aqueous solution