BMP7 overexpression in adipose tissue induces white adipogenesis and improves insulin sensitivity in ob/ob mice.

Estefania CasanaVeronica JimenezVictor SacristanSergio MuñozClaudia JambrinaJordi RodóMiquel GarciaCristina MallolXavier LeónSylvie FranckhauserFatima Bosch

Published in: International journal of obesity (2005) (2020)

This study unravels a new autocrine/paracrine role of BMP7 on white adipogenesis and highlights that BMP7 may modulate WAT plasticity and increase insulin sensitivity.

Keyphrases

mesenchymal stem cells
high fat diet induced
adipose tissue
bone regeneration
insulin resistance
cell proliferation
type diabetes
bone marrow
metabolic syndrome
skeletal muscle
wild type