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Sustained QTc Prolongation During Recovery from Hypoglycemia in People with Type 1 Diabetes, Independently of Recovery to Hyper- or Euglycemia.

Christine R AndreasenAndreas AndersenPer G HagelqvistKaisar MaythamJulius V LauritsenSusanne EngbergJens FaberUlrik Pedersen-BjergaardFilip K Krag KnopTina Vilsbøll
Published in: Diabetes, obesity & metabolism (2023)
In people with type 1 diabetes, insulin-induced hypoglycemia prolongs cardiac repolarization, which is sustained during a 60-minute recovery period independently of recovery to hyperglycemia or euglycemia. Thus, vulnerability to serious cardiac arrhythmias and sudden cardiac death may extend beyond a hypoglycemic event, regardless of hyperglycemic or euglycemic recovery. This article is protected by copyright. All rights reserved.
Keyphrases
  • type diabetes
  • left ventricular
  • glycemic control
  • heart failure
  • drug induced
  • skeletal muscle
  • oxidative stress
  • atrial fibrillation
  • weight loss