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Isolation and characterization of high affinity and highly stable anti-Chikungunya virus antibodies using ALTHEA Gold Libraries™.

M Pedraza-EscalonaO Guzmán-BringasH I Arrieta-OlivaK Gómez-CastellanoJ Salinas-TrujanoJ Torres-FloresJ C Muñoz-HerreraR Camacho-SandovalP Contreras-PinedaR Chacón-SalinasS M Pérez-TapiaJuan C Almagro
Published in: BMC infectious diseases (2021)
The newly discovered antibodies offer valuable tools for characterization of CHIKV isolates. Therefore, the strategy here followed using whole viral particles and ALTHEA Gold Libraries™ could expedite the discovery and development of antibodies for detection and control of emergent and quickly spreading viral outbreaks.
Keyphrases
  • sars cov
  • zika virus
  • small molecule
  • high throughput
  • dengue virus
  • genetic diversity