Real-world clinical and virological outcomes in a retrospective multiethnic cohort study of 341 untreated and tenofovir disoproxil fumarate-treated chronic hepatitis B pregnant patients in North America.
Golasa Samadi KochaksaraeiEliana CastilloMatthew D SadlerCynthia H-T SeowHerman W BarkemaSteven R MartinHeidi IsraelsonJacqueline PintoSarah WilliamsAIexander I AspinallLaura M StintonMeredith A BormanKelly W BurakMark G SwainStephen E ConglySamuel S LeeAbdel Aziz ShaheenCarla S CoffinPublished in: Alimentary pharmacology & therapeutics (2020)
Post-partum ALT flares were common, especially after TDF withdrawal. Overall, 37% achieved HBeAg clearance and 2.9% had HBsAg loss during long-term follow-up.