Precise NMR Method for Titering Organometal Reagents.

Vineet K JakharEric C JohnsonAditya KavuturuJessica K HellerAdam S Veige Ion Ghiviriga

Published in: Organic letters (2021)

The concentration of organometal reagents can be conveniently determined by obtaining the NMR spectra of the neat reagent solution, and, in a second NMR tube, of a neat reference solvent. The PULCON relationship, implemented in all major NMR software, is then used to calculate the concentration of the reagent based on the absolute integrals in the spectra, the known concentration of the reference, and the number of protons under the integrals.

Keyphrases

solid state
magnetic resonance
high resolution
density functional theory
data analysis
molecular dynamics