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Edge-wise analysis reveals white matter connectivity associated with focal to bilateral tonic-clonic seizures.

Sam S JavidiXiaosong HeAnkeeta AnkeetaQirui ZhangSalvatore CitroMickael R SperlingJoseph I Tracy
Published in: Epilepsia (2024)
Data showed that not all STR pathways are equally affected by the seizure propagation of FBTCS. We demonstrated two key biases, one indicating a large role for the amygdala in the propagation of seizures, the other pointing to the prominent role of cross-hemispheric and contralateral hemisphere connections in FBTCS. We demonstrated topographic reorganization in FBTCS, pointing to the specific WM tracts involved.
Keyphrases
  • white matter
  • temporal lobe epilepsy
  • multiple sclerosis
  • functional connectivity
  • resting state
  • electronic health record
  • big data
  • case report
  • artificial intelligence
  • stress induced