PDE5A Suppresses Proteasome Activity Leading to Insulin Resistance in C2C12 Myotubes.
Wei LiuXiaojun TianTi WuLe LiuYanghongyun GuoChanghua WangPublished in: International journal of endocrinology (2019)
These results suggest that PDE5A suppresses proteasome activity, which results in ER stress and subsequent insulin resistance in C2C12 myotubes.
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