Function of mast cell and bile-cholangiocarcinoma interplay in cholangiocarcinoma microenvironment.

Anda ShiZengli LiuZhongqi FanKangshuai LiXingkai LiuYongchang TangJiaming HuXingyong LiLizhuang ShuLiming ZhaoLingling HuangZhiyue ZhangGuo-Yue LvZongli ZhangYun-Fei Xu

Published in: Gut (2024)

Bile HA is released from MCs through DMPD stimulation and degraded via SLC22A3 import. Different HA receptors exhibit a distinct expression profile in CCA and produce different oncogenic effects. MCs promote CCA progression in a CCA-bile interplay pattern.

Keyphrases

stem cells
transcription factor