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Utility of Circulating Free DNA Fragmentomics in the Prediction of Pathological Response after Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.

Yaqi WangXiaojun FanHua BaoFan XiaJuefeng WanLijun ShenYan WangHui ZhangYulin WeiXue WuYang ShaoXinxiang LiYe XuSanjun CaiZhen Zhang
Published in: Clinical chemistry (2022)
The combination of a 5'-end motif profile with mrTRG has the potential to predict the response to nCRT, and therefore may improve the patient selection for a W&W approach.
Keyphrases
  • rectal cancer
  • locally advanced
  • neoadjuvant chemotherapy
  • phase ii study
  • circulating tumor
  • case report
  • squamous cell carcinoma
  • cell free
  • single molecule
  • radiation therapy